Agaricus Blazei Murill success against Cancer.

Agaricus originates from Piedade, which is located in the suburbs of Sao Paulo, Brazil. The climatic conditions in Piedade include temperatures that soar to 35-38 0C during the day and dip to between 20-25 C at night, with the humidity that averages 80%. The place also experiences regular squall toward evening. Agaricus Blazei Murill Mushroom (ABM) thrives only under these conditions, suggesting that its survival is significantly affected by these external conditions.

Around the same time, ABM Mushroom was introduced to Japan. Dr. Shoji Shibata, who at the time was a professor in the harmacological Department of Tokyo University, and Dr. Tetuo Ikegawa of the National Cancer Center, jointly I researched the pharmacological effects of 4 Agaricus. The research results were released at the general convention of the Japan Pharmacological Association and the Japan Cancer Association. The experience with mice verified that the polysaccharide beta-D-glucan contained in 4 Agaricus significantly activated the immune system.

The polysaccharide contained in Agaricus Blazei Murill vitalizes production of interferon and interleukin in small animals (guinea pigs). This effect indirectly functions to destroy or prevent the proliferation of cancer cells. This refers to a cytokine inducing effect. Moreover, the experiments conducted by the researchers named above proved that this effect can also prevent viruses and other external factors from entering the tissue.

Clinical results obtained in collaboration with university researchers and hospital since the report on the anti cancer effect of Agaricus Blazei Murril (ABM Mushroom) was released at the general convention of the Japan Cancer Association in 1980 proved that although many fungi polysaccharide only effect solid cancer and polysaccharide of Agaricus Blazei Murril is effective against Ehrlich’s ascites carcinoma sigmoid colonic cancer, ovarian cancer, breast cancer, lung cancer, and liver cancer as well as against solid cancer.

The results of the experiments suggest that it also activates metabolism by revitalizing normal biological tissue. Digestive enzymes such as amylase trypsin martase and the protease contained in fungus also enhances digestion. Furthermore, tyrosinase, an enzyme which oxidizes tyrosine and produces melanin, has a hypotensive effect.

Living organisms are equipped with immunity system which expels pathogens, toxic chemicals and tumorous cells generated through mutation. When tumorous cells attach to form a simple protein lump, it is Decomposed by microorganisms such as bacteria. Thanks to this function, which is called immunity, bodies can maintain their health by fighting off harmful microorganisms, stopping them from entering tissue or
discharging them from tissue.

The human immune system is comprised of more that 130 subsets of white blood cells. About 15% of them are called Natural Killer (NK) cells, These provide the first line of defense for dealing with any form of
invasion to the body. Each cell contains several small granules which act as ‘ammunition.’ When an NI( cell recognizes a cancer cell, for instance, it attaches itself to the cells outer membrane and inject these granules directly into the interior of the cell.

More specifically, natural killer cells or NK cells play a critical role neutralizing outside organisms such as viruses and bacteria that enter the body. Through a process called phagocytosis, the NK cells “kiss” and
engulf foreign agents and release toxic chemicals that destroy them.

In cancer patients, the NK cells and cancer cells constantly baffle one another. The NK cells attempt to destroy cancer cells while at the same time cancer cells try to neutralize NK cells before they can harm them. If the NK cells are weak or if there are not enough NK cells in the body, the cancer spreads through- out the body resulting in death. Several factors contribute to this weakening of the immune system: most notably stress, age, pollution, and smoking

When their immune systems work properly, humans remain healthy. However, the immune systems in many people are weakened by stress, poor eating habits and pollution, such as air pollution. These people can suffer from a number of diseases.

It is widely believed that cancer is caused by a decline in the immune system caused by aging and other factors. It is also known that atopic dermatitis asthma, pollinosis and rheumatism result from an excessive immuno reaction. The AIDS virus destroys immune cells and triggers diseases.

Agaricus Blazei Murill, which is enjoying growing attention, contains a large amount of polysaccharide, which is believed to enhance immunity. It does not only bolster immunity but reduces excessive immuno reactions to maintain a balance. Of all fungi, ABM Mushroom is particularly rich in polysaccharide, and has shown particularly strong results in treating and preventing cancer. We believe that Agaricus Blazei Murril is the ideal food for the people of today, who are exposed to a difficult living




Mizuno, T., Hagiwara, T., Nakamura, T., Ito, H. Shimura, K. Suuuya, T., Asakura, A, 1990. Antituxnor activity and some prupcrties of water-insoluble hmtro-glyc.ns from “Himaiuatsutako,” the fruiting body of
Agaricus blnzei Murill, Agricultural & Biological Chemistry 54. Tokyo. pp. 2897-2905.

Ito, H., K. Shimura, H. Itoh, M. Kawade, 1997. “Autitumor effects of a new polysacobaride-pratem complex (ATOM) prepared from Agai-icus blazei (Jwadc strain 101) “Himematsutake” and its mechanisms iii tumor-bearing mice” Anticancer Research Jan-Feb 1 7( 1A): 277-84.

Itoh, H., H, Ito, H. Amino, and H. Nod., 1994. “Inhibitory action of a (l–>6)beta-D-glucan-protein
complex (P111-2-b) isolated from Agaricns blazci MurilI (“Hiinematautske”) on Moth A fibrosarcoma- bearing mice and its antitumor mechanism” Japanese Journal of Pharmacology Oct; 662): 265-7 1.

Kawagishi, H., A. Nomura, T. Yunien, T. Mizuno~ I. Hagwara and T. Nakamura, 1988. “Isolation and properties of a lectin from the fruiting bodies of Agaricus blazei” Carbohydrate Research Nov 15: 183(1): 150-4.

Kawagishi, H., R. lnagaki, T. Kanao, T. Mizuno, lC~ Shinmra, H. Ito, T. Hagiwara, and T. Nakamura, 1989. “Fractionation and aniitumor activity of the water insoluble residue of Agaricua blazei fruiting bodies Carbohydrate Research Mar. 15; 186(2): 267-73.

Mizuno, T, Hagiwara, T., Nakamura, 1., Ito, H, Shiniurs, K. Sumiya, T., Aaakura, A. 1990. “Antitumor activity and some properties of water-soluble polysaccbarides from ‘Himematsutnke,’ the fruiting body of Agancus blazei Murrifl” Agricultural & Biological Chemistry 54. Tokyo. 2889-2896.

Osakl, Y., T. Kato, K. Yamamto, 1. Okubo, T. Mlyankl, 1994. “Antlmutagenlc and bactericidal
substances In the fruit body of a Basldlomycete Agarlcus blazel” Journal of the Pharmaceutical
Society of Japan May; 114(5): 342.50

Mizuno, T, H. Ito, K, Shirnura, T. Hagiwara & T, Nakamura, 1989. “Preparation method of antitwnor neutral polysacchsrides from Himematsutake” Japan Kokai Tokkyo Koho (A), ShoG4-67 195, March 13, 56$568.

Mizuno, T, H. Ito, K. Shmtura, T. Hagiwara & T. Nakamura, 1989. “PreparatIon method of antitunior acidic glycanz from Himematcutake” Japan Kokai Tokkyo Kobo (A), Sho64-67 194, Match 13, 561-564.

Lions Mane Mushroom on Alzheimer’s disease and Dementia.

Anti-Dementia Compounds from Lion’s Mane Mushroom

The focus of research on medicinal mushrooms until now has been primarily on their anti-cancer and immune-enhancing properties. However, attention has shifted by researchers in Japan and China to the potential anti-dementia properties contained in a mushroom called Lion’s Mane (Hericium erinaceus).

A study was done in a rehabilitative hospital in the Gunma prefecture in Japan, with 50 patients in an experimental group and 50 patients used as a control. All patients suffered from cerebrovascular diseases causing senility, Parkinson’s disease, or other spinocerebellar and orthopedic diseases that afflict the elderly. Seven of the patients in the experimental group suffered from different types of dementia.

The patients in this group received 5g of dried Lion’s Mane Mushroom per day in their soup for a 6-month period. All patients were evaluated before and after the treatment period for their Functional Independence Measure (FIM), which is a measure of independence in physical capabilities (eating, dressing, walking, etc) and perceptual capacities (understanding, communication, memory, etc).

The results of this preliminary study show that after six months of taking Lion’s Mane Mushroom, six out of seven Alzheimer’s patients demonstrated improvements in their perceptual capacities, and all seven had improvements in their overall FIM score.

In 1991, a novel class of compounds in Lion’s Mane, called “hericenones”, was discovered by Dr. Hirozaku Kawagishi of Shizuoka University in Japan. These “hericenones” were found to stimulate the production of Nerve Growth Factor (NGF) in mouse astraglial cells in culture. Dr. Kawagishi saw the possibility of using this novel compound as a natural treatment for Alzheimer’s disease. He speculated that if they could cross the blood-brain barrier and induce NGF production in the brain, this might counteract some of the neurodegenerative effects of Alzheimer’s disease. Massive neuronal cell death is the ultimate outcome of Alzheimer’s disease, so NGF production might conceivably lead to the growth of new neurons to replace those that die.

Dr. Kawagishi’s continuing work on “hericenones” led him to pursue more deeply the mechanism by which damage is done in Alzheimer’s disease. As the disease progresses, there is destruction of neurons caused by the formation of plaques containing a molecule called amyloid beta peptide. These plaques are toxic to surrounding neurons in the brain. Dr. Kawagishi discovered that an agent in Lion’s Mane Mushroom inhibits the toxicity of the plaques. He demonstrated that this agent is a phospholipid and can exert a protective effect on brain cells in culture, shielding them from damage by the amyloid peptides. This agent is now called Amyloban (Japanese patent 394,3399).


Source: Shokos

Medicinal mushrooms and weight loss


Products which help with weight loss are abundant. One issue is these food items are not usually included in a regular eating routine. Junk, processed and fast food items tend to be an average diet. Rather, an ordinary diet should contain food items which are homemade, natural and nutritious.

Processed, fast and junk food products normally are abundant with calories, saturated fats and simple carbs. This fat is located in shortening, margarine and hydrogenated oil. Simple carbs are found in buns, breads and muffins. Additionally, junk, processed and fast foods usually furnish small amounts of antioxidants, vitamins and minerals. Thus, dining on junk, fast and processed foods furnishes huge quantities of food calories however hardly any nutriments. Regular intake of junk, fast and processed foods brings about excessive pounds as well as health conditions. Therefore, whenever feasible try and watch consumption of these food products.

A wonderful food to lose weight is a mushroom, for example shiitake, maitake and reishi. These foods supply a number of valuable nutrients that help in reducing pounds. Plus, mushrooms have small amounts of calories. Hence, eating mushrooms does not cause excessive weight.

Besides assisting in reducing pounds, shiitake, reishi and maitake mushrooms provide health advantages. Studies have proven shiitake mushrooms will lower blood pressure, reduce cholesterol and heal infections. Studies have proven maitake mushrooms can treat cancer, prevent cancer and control blood sugar. In addition, this mushroom has been shown they can reduce blood pressure. Reishi mushrooms are used for a variety of ailments like cancer, inflammation, heart disease and ulcers. Plus, reishi mushrooms have anti-microbial components that could inhibit HIV.

There consist of quite a few techniques for adding mushrooms in healthy, homemade and scrumptious foods. Mushrooms are generally added in eggs, soups and pasta dishes. Also, mushrooms can be added on top of salads, meats and pizzas. Therefore, making healthy, homemade and scrumptious foods that assist with weight loss utilizing mushrooms will be simple.

A few individuals might not like the taste when eating reishi, shiitake and maitake mushrooms. Therefore, if eating a mushroom is not desired, a different choice is taking a vitamin supplement or an extract, so those valuable nutrients are ingested.

Even though typical eating routines include fast, junk and processed food products, reducing excess weight will be tough consuming those kinds of food products regularly. Including mushrooms packed with nutriments in eating routines will be beneficial whenever trying to eliminate unwanted weight. Nutrients are important concerning weight loss because a human body must have abundant nutrients to function effectively.


Reishi mushroom and Candida


Reishi Mushroom Extract and other Medicinal Mushrooms Benefit Candida Sufferers!

Reishi Mushrom Extract is a Beneficial Candida Treatment!

There seems to be a constant babble about whether people with candida overgrowth should avoid mushrooms for the sake of their health. Most people, including “experts” will tell you not to consume mushrooms of any kind.

Let’s set the record straight.

Although they fall under the same general category of fungi: Mushrooms are not mold. Mushrooms are not yeast.

Not all mushrooms need be avoided.

The ones you do want to enjoy include shiitake, maitake (both culinary delights) and reishi mushrooms (not so delicious, usually taken as reishi mushroom extract). In fact, reishi mushrooms can help your immune system to regain balance over the invasive form of candida. Remember, candida is a natural element in the human body, it only becomes invasive and detrimental when it is given an opportunity to grow out of control, which happens when the immune system is weakened.

“Candida and Mushrooms? I’ve heard to avoid mushrooms if my health is suffering due to candida overgrowth.”

I know, me too! But for many years I’ve known about the healing effects of shiitake and reishi mushrooms. I ate shiitakes while I was doing my cleanse diet, and never felt any ill effects.

Finally I’ve been taking the time to research it more for myself and my results are really pleasing! Here is some of the encouraging information I’ve been gathering about reishi mushroom extract, maitake and shiitake mushrooms:

Did you know that some fungi are more closely related to animals than plants are to those same animals? And that some diseases which affect fungi can affect humans as well? I didn’t until recently. Weird, but true.

For instance, three pathenogenic microorganisms which cause diseases common to fungi and humans (these are ones I know of, I’m sure there are more):

Escherichia coli (E Coli)
Staphylococcus aureus (the most common cause of staph infections)
Pseudomonas aeruginosa (a bacteria which causes the common “hot tub rash, or “hot tub folliculitis”)
One of medicinal mushrooms’ natural defenses is to produce antibiotics to fight infection from microorganisms. In fact, antibiotics commonly prescribed at the doctor’s office are often derived from fungi.

There is an increasingly accepted hypothesis in modern medicine that polypore mushrooms like reishi mushroom extract and maitake mushrooms can help provide a immune “shield” against a number of infectious diseases, including candida. Shiitake mushrooms, while not polypores, are also known for their immune enhancing properties.

One of the beneficial elements in these medicinal mushrooms are certain polysaccharides, which are a form of complex carbohydrates. Cellulose (plant fiber) and pectin (found in fruits such as citrus, apples and pears) are two other well known forms of polysaccharides.

Okay, once again, let me reiterate that I’m no scientist, but I am an avid reader and always poking around for new and interesting information. Here’s some more information I’ve dug up on reishi mushrooms and other healing mushrooms – some of which even I wouldn’t attempt to explain scientifically, but nonetheless I find it compelling because there is an abundance of scientific and medicinal research coming back with positive results.

Reishi Mushrom Extract and other Medicinal Mushrooms Are Beneficial For Numerous Reasons
Reishi mushrooms and the other healing mushrooms contain an abundance of not only “polysaccharides” but also “protein-bound polysaccharides”, including the much touted beta-D-glucans, which is one reason they all possess such potent immune-strengthening properties (beta-D-glucans is primarily used for immune enhancing properties as well as its ability to help lower cholesterol).

Other medicinal herbs and plants including Aloe Vera, Echinacea and Astragalus contain polysaccharides, which are believed to be a major part of their immune-enhancing actions. Protein-bound polysaccharides found in the medicinal mushrooms have been shown to be even more effective for immune responses than individual polysaccharides.

Thus, it’s hypothesized that the protein-bound polysaccharides found in mushrooms such as reishi mushroom extract, maitake mushrooms and shiitake mushrooms are extra-beneficial for people whose health is compromised by candida overgrowth.

Animal and human trials demonstrate that mushrooms like reishi, maitake and shiitake enhance the production of T-cells, helper T-cells, natural killer cells and macrophages.

They also contain sterols and triterpenes which have been demonstrated to help lower blood pressure and serum cholesterol levels as well as reduce inflammatory responses.

They’ve also been shown to protect and enhance liver function, which is great news for candida sufferers, since the liver is working overtime to process the toxins produced by the candida yeasts.

All mushrooms are surprisingly rich in protein and B vitamins (which help to relieve stress, depression and fatigue commonly associated with candida and poor health in general).

They’re also the only non-animal source of vitamin D that I know of. The USDA’s recommended daily intake of Vitamin D is 200 IU (international units), which is considered a very low estimate by numerous health experts. All mushrooms synthesize vitamin D from natural sunlight (or even artificial light), but look at the comparison between regular button mushrooms and shiitake mushrooms:

100 grams of white button mushrooms contain an average of 18 IU of vitamin D.

100 grams of shiitake mushrooms contain an average of 96 IU of vitamin D!!

Vitamin D deficiency is being linked to many health problems, so make sure you’re getting enough every day. Remember, vitamin D is synthesized by the body from sunlight, or obtained from food sources like cod liver oil, salmon, eggs, milk.

Or… from the shiitakes in your stir fry… Yum!!

I could go on, but I hope instead that these notes will encourage more readers to consider the benefits of Reishi mushroom, as well as cooking with maitake and shiitake mushrooms for candida, health and overall wellness.